Skin whitening | Cosmetics & Makeup | Skin, Acid, Vitamin, Melanostat, Melanin

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Skin whitening

Skin whitening is a term covering a variety of cosmetic methods used to whiten the skin . Most skin whiteners currently on the market contain ingredients (hydroquinone, ascorbic acid, kojic acid, arbutin, azealic acid, glycyrrhetinic acid (licorice extract)) that act as direct inhibitors of tyrosinase, the enzyme in the skin pigment cells (melanocytes) that make melanin.

Arbutin is very safe skin agent for external use which does not have toxicity, stimulation, unpleasant odor or side effect such as Hydroqinone. There is an increasing awareness that vitamin C has a wide variety of role in human health. New therapeutic uses are being investigated daily, among recent discoveries is that Vitamin C can play important role in the health and beauty of your skin. As we grow older, we suffer diminished micro capillary circulation within our skin, which deprives our skin cells of the supply of vitamin C it needs for youthful collagen synthesis.

The topical application of vitamin C in a skin-penetrating medium can dramatically enhance the availability of vitamin C for collagen production. Vitamin C regenerates vitamin E and enables vitamin E to provide sustained antioxidant protection in the skin's elastin fibers. As a fungal metabolic product, kojic acid inhibits the catecholase activity of tyrosinase, which is the rate-limiting, essential enzyme in the biosynthesis of the skin pigment melanin. Kojic acid also is consumed widely in the Japanese diet with the belief that it is of benefit to health. Melanocytes treated with kojic acid become nondendritic with a decreased melanin content. Additionally, it scavenges reactive oxygen species that are excessively released from cells or generated in tissue or blood.

Natural Skin Whitening System is the safest, fastest, and most natural method available for whitening overall skin color and fading age spots, liver spots, freckles, hyper-pigmentations and skin discolorations. It is especially popular in Eastern Asian countries, but is also used in parts of Latin America , Southern Africa , Mauritius and the United States. This tyrosinase inhibitor was isolated from a plant herbal extract. Melanostat is a peptide obtained by amino acid synthesis with a technique of Merryfield.

The target of Melanostat the membrane receptor of alpha-MSH on the melanocytes, the B- MICR receptor , its mode of action is a competitive inhibition of membrane receptors are blocked in a natural way. Melanostat counterbalances the formation of melanin and especially the synthesis of tyrosinase, key enzyme involved in the process of pigmentation.

In the skin, plays an essential role in the stimulation of the synthesis of melanin. Recently, researches performed on enabled a detailed study of the structure and function of this molecule, so as the exact determination of its receptor. The study of these molecules enabled researchers to synthesize peptides with a similar (msh-like), or antagonist activity. Because of this similarity, Melanostat acts while competing the receptors on the melanocytes. The incorporation of Melanostat in skin lightening creams will place the skin in a physiological dominan situation. Its action is based on the reinforcement of the natural ability of the skin to counteract the activity of alpha-MSH.

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