These are the only products that have been studied for safety and effectiveness and approved by FDA for treating signs of sun-damaged or aging skin:

• Renova (tretinoin emollient cream). This vitamin A derivative, available by prescription only, is approved for reducing the appearance of fine wrinkles and mottled darkened spots and roughness of facial skin in people whose skin does not improve with regular skin care and use of sun protection. Renova does not eliminate wrinkles, repair sun-damaged skin, or restore skin to its healthier younger structure. Also, the safety of daily Renova use for longer than 48 weeks has not been established, and it should not be used by women who are pregnant or trying to become pregnant. Renova has not been studied in people 50 and older or in people with moderately or darkly pigmented skin.
• Carbon dioxide (CO2) and Erbium:YAG (Er:YAG) lasers. These medical devices are approved for treating wrinkles. The procedure requires removal of facial skin in a layer-by-layer manner. It is performed under anesthesia by a doctor in an outpatient surgical setting.

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